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How self-reactive immune cells are allowed to develop

Joan Yuan, research team leader at the Department of Laboratory Medicine. Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive – they produce not only antibodies against foreign substances, but also against the body’s own substances, and it is unclear why the immune system allows for the development of these particular cells. Now a research team at Lund University in Sweden has found the mechanism that controls the growth of B1-cells in mice. The findings, which may lead to a deeper understanding of certain forms of cancer and autoimmune diseases, was recently published in the journal Science Immunology.

Think tank seeks solutions for the Health crisis

Jan Nilsson, Professor in Cardiovascular Research and Chair of the new think tank Vård och Vetenskap Swedish health care delivers good results, yet we hear every day about the health crisis and its consequences. Now, representatives of academia and health care have grown tired of the crises and started the think tank Health Care and Science with the goal of contributing to solutions and spreading good ideas. – We want to create better health care by strengthening the relationship between health care and science, says Jan Nilsson, professor of experimental cardiovascular research at Lund University and chair of the think tank.

Translational research: Developing new methods to prevent organ rejection and growing new organs in the lab

Darcy Wagner and Sandra Lindstedt Ingemansson, researchers at the Wallenberg Center for Molecular Medicine, Lund University and Skåne University Hospital. Photo: Agata Garpenlind 800 people in Sweden are currently on the waiting list to receive donated organs, but there are too few organs. Nearly one person dies each week in Sweden while on the waiting list. How can this lack of donor organs in Sweden be solved? Researchers Darcy Wagner, Department of Experimental Medical Science, and Sandra Lindstedt Ingemansson, Department of Clinical Science Lund and Skåne University Hospital, both connected to the Wallenberg Center for Molecular Medicine (WCMM) at Lund University, are looking for solutions in their labs.

From carpets in the market to Academy professor

William Agace, Professor at Mucosal Immunology at Dep. of Experimental Medical Science at Lund University. Photo: Agata Garpenlind He was selling carpets on Mårtenstorget in Lund, applying for all kinds of jobs and answered an advert from the Department of Clinical Immunology, Lund University, for a lab technician job. He didn´t get the job. Instead he was asked if he wanted to start a Ph.D. A few weeks ago immunology professor William Agace was elected a member of the Royal Swedish Academy of Sciences. He invited me to his carpet for at scientific chat.

The power of networking within life science

Öresund Bridge On 4 November there is an opportunity for researchers at Lund University to participate free of charge in the annual meeting of the Medicon Valley Alliance. Petter Hartman, CEO, talks about the benefits for both society and individual researchers when life science networks are strengthened and cooperation flourishes across national boundaries.

Reversing Muscle Dystrophy

Kinga Gawlik, researcher at the Dep. of Experimental Medical Science. Photo: Agata Garpenlind A new technology has brought researchers one step closer to a future cure for Congenital Muscular Dystrophy type1A, a devastating muscle disease that affects children. The new findings are based on research by Kinga Gawlik at Lund University, Department of Experimental Medical Science, and were recently published in Nature.

An additional SEK 50 million to research on the brain’s mechanisms

Illustration: Brain with cogwheels A European consortium, led from Lund University, is to receive SEK 50 million from the EU for research which is to develop our understanding of the functional mechanisms of the brain. The research project, called INTUITIVE, is one of the Innovative Training Networks within the framework of Horizon 2020.